Clomiphene Online



How and where to order Clomid (Clomifene Citrate) 25 mg, 50 mg, 100 mg tablets or capsules online on Colorado Infertility Doctors:

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Prices:from $0.37 per pill
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Forms:25 mg, 50 mg, 100 mg tablets
Quantity:30-360 pills
Type:Clomiphene brand, Fertomid brand, Clomid generic, Serophene generic
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Clomiphene Citrate (USAN) or Clomifene Citrate (INN) (trade names include Clomid, Fertomid, Serophene, Clofert, Clomhexal, Clomifen, Clomifene, Clomifeno, Clostilbegyt, Fertyl, Ikaclomin, Omifin, Ova-Mit, Ovinum, Ovofar, Ovulet, Pergotime, Prolifen, Siphene) is a well-known and commonly prescribed fertility medication from synthetic ovulation stimulants pharmacological group. This medicine is used to increase the chance of getting pregnant, for treating female infertility (ovulatory dysfunction) by helping women ovulate (produce a mature egg) properly during their cycle. Sometimes clomiphene is prescribed to men with fertility problems due to low sperm counts.


Clomiphene Citrate (Clomid) tablets


Related medications:

  • Bromocriptine (Parlodel)
  • Butylscopolamine (Buscopan)
  • Cabergoline (Dostinex)
  • Clotrimazole (Gyne-Lotrimin)
  • Cyclofenil (Fertodur)
  • Danazol (Danocrine)
  • Dydrogesterone (Duphaston)
  • Eflornithine (Vaniqa)
  • Epimestrol (Stimovul)
  • Estradiol (Estrace)
  • Estrogens conjugated (Premarin)
  • Exemestane (Aromasin)
  • Ibandronate (Boniva)
  • Medroxyprogesterone (Cycrin)
  • Norethindrone (Norlutate)
  • Norethisterone (Aygestin)
  • Progesterone (Prometrium)
  • Raloxifene (Evista)
  • Tamoxifen (Nolvadex)


    Pharmacological and medical categories:

  • Estrogen agonist-antagonists
  • Ovulation stimulation drugs
  • Trophic hormones and related synthetic drugs
  • Medications for the treatment of female infertility
  • Men's health
  • Women's health


    ATC codes:

  • G - Genito urinary system and sex hormones
  • G03 - Sex hormones and modulators of the genital system
  • G03G - Gonadotropins and other ovulation stimulants
  • G03GB - Ovulation stimulants, synthetic
  • G03GB02 - Clomifene


    ICD-10 codes:

  • Ovarian dysfunction - E28
  • Male infertility - N46
  • Other disorders of breast - N64
  • Absent, scanty and rare menstruation - N91
  • Female infertility - N97


    Indications and usage:

    Clomid (Clomiphene Citrate) tablets are indicated for the treatment of ovulatory dysfunction in women desiring pregnancy. Impediments to achieving pregnancy must be excluded or adequately treated before beginning Clomid therapy. Those patients most likely to achieve success with clomiphene therapy include patients with polycystic ovary syndrome, amenorrhea-galactorrhea syndrome, psychogenic amenorrhea, post-oral-contraceptive amenorrhea, and certain cases of secondary amenorrhea of undetermined etiology.

    Properly timed coitus in relationship to ovulation is important. A basal body temperature graph or other appropriate tests may help the patient and her physician determine if ovulation occurred. Once ovulation has been established, each course of Clomiphene (Clomid) should be started on or about the 5th day of the cycle. Long-term cyclic therapy is not recommended beyond a total of about six cycles (including three ovulatory cycles).

    Clomid tablets are indicated only in patients with demonstrated ovulatory dysfunction who meet the conditions described below:

  • Patients who are not pregnant.
  • Patients without ovarian cysts. Clomiphene Citrate (Clomid) should not be used in patients with ovarian enlargement except those with polycystic ovary syndrome. Pelvic examination is necessary prior to the first and each subsequent course of Clomid treatment.
  • Patients without abnormal vaginal bleeding. If abnormal vaginal bleeding is present, the patient should be carefully evaluated to ensure that neoplastic lesions are not present.
  • Patients with normal liver function.

    In addition, patients selected for Clomid therapy should be evaluated in regard to the following:

  • Estrogen Levels. Patients should have adequate levels of endogenous estrogen (as estimated from vaginal smears, endometrial biopsy, assay of urinary estrogen, or from bleeding in response to progesterone). Reduced estrogen levels, while less favorable, do not preclude successful therapy.
  • Primary Pituitary or Ovarian Failure. Clomiphene therapy cannot be expected to substitute for specific treatment of other causes of ovulatory failure.
  • Endometriosis and Endometrial Carcinoma. The incidence of endometriosis and endometrial carcinoma increases with age as does the incidence of ovulatory disorders. Endometrial biopsy should always be performed prior to Clomid therapy in this population.
  • Other Impediments to Pregnancy. Impediments to pregnancy can include thyroid disorders, adrenal disorders, hyperprolactinemia, and male factor infertility.
  • Uterine Fibroids. Caution should be exercised when using Clomiphene in patients with uterine fibroids due to the potential for further enlargement of the fibroids.

    There are no adequate or well-controlled studies that demonstrate the effectiveness of Clomid pills in the treatment of male infertility. In addition, testicular tumors and gynecomastia have been reported in males using clomiphene. The cause and effect relationship between reports of testicular tumors and the administration of Clomid is not known.

    Although the medical literature suggests various methods, there is no universally accepted standard regimen for combined therapy (ie, Clomid in conjunction with other ovulation-inducing drugs). Similarly, there is no standard Clomiphene tablets regimen for ovulation induction in in vitro fertilization programs to produce ova for fertilization and reintroduction. Therefore, Clomid tablets are not recommended for these uses.


    Dosage and administration:

    General Considerations

    The workup and treatment of candidates for Clomid (Clomiphene Citrate) tablets therapy should be supervised by physicians experienced in management of gynecologic or endocrine disorders. Patients should be chosen for therapy with Clomid only after careful diagnostic evaluation. The plan of therapy should be outlined in advance. Impediments to achieving the goal of therapy must be excluded or adequately treated before beginning Clomid. The therapeutic objective should be balanced with potential risks and discussed with the patient and others involved in the achievement of a pregnancy.

    Ovulation most often occurs from 5 to 10 days after a course of Clomid. Coitus should be timed to coincide with the expected time of ovulation. Appropriate tests to determine ovulation may be useful during this time.

    Recommended Dosage

    Treatment of the selected patient should begin with a low dose, 50 mg daily (1 tablet) for 5 days. The dose should be increased only in those patients who do not ovulate in response to cyclic 50 mg Clomid. A low dosage or duration of treatment course is particularly recommended if unusual sensitivity to pituitary gonadotropin is suspected, such as in patients with polycystic ovary syndrome.

    The patient should be evaluated carefully to exclude pregnancy, ovarian enlargement, or ovarian cyst formation between each treatment cycle.

    If progestin-induced bleeding is planned, or if spontaneous uterine bleeding occurs prior to therapy, the regimen of 50 mg daily for 5 days should be started on or about the 5th day of the cycle. Therapy may be started at any time in the patient who has had no recent uterine bleeding. When ovulation occurs at this dosage, there is no advantage to increasing the dose in subsequent cycles of treatment.

    If ovulation does not appear to occur after the first course of therapy, a second course of 100 mg daily (two 50 mg tablets given as a single daily dose) for 5 days should be given. This course may be started as early as 30 days after the previous one after precautions are taken to exclude the presence of pregnancy. Increasing the dosage or duration of therapy beyond 100 mg/day for 5 days is not recommended.

    The majority of patients who are going to ovulate will do so after the first course of therapy. If ovulation does not occur after three courses of therapy, further treatment with Clomid is not recommended and the patient should be reevaluated. If three ovulatory responses occur, but pregnancy has not been achieved, further treatment is not recommended. If menses does not occur after an ovulatory response, the patient should be reevaluated. Long-term cyclic therapy is not recommended beyond a total of about six cycles.


    Overdosage:

    Signs and symptoms

    Toxic effects accompanying acute overdosage of clomiphene have not been reported. Signs and symptoms of overdosage as a result of the use of more than the recommended dose during CLOMID therapy include nausea, vomiting, vasomotor flushes, visual blurring, spots or flashes, scotomata, ovarian enlargement with pelvic or abdominal pain.

    Oral LD50: The acute oral LD50 of clomiphene is 1700 mg/kg in mice and 5750 mg/kg in rats. The toxic dose in humans is not known.

    Dialysis: It is not known if clomiphene is dialyzable.

    Treatment

    In the event of overdose, appropriate supportive measures should be employed in addition to gastrointestinal decontamination.


    Contraindications:

  • Hypersensitivity. Clomid is contraindicated in patients with a known hypersensitivity or allergy to clomiphene citrate or to any of its ingredients.
  • Pregnancy. Pregnancy Category X. Clomid pills use in pregnant women is contraindicated, as Clomiphene does not offer benefit in this population.
    Available human data do not suggest an increased risk for congenital anomalies above the background population risk when used as indicated. However, animal reproductive toxicology studies showed increased embryo-fetal loss and structural malformations in offspring. If this drug is used during pregnancy, or if the patient becomes pregnant while taking this drug, the patient should be apprised of the potential risks to the fetus.
  • Liver Disease. Clomid therapy is contraindicated in patients with liver disease or a history of liver dysfunction.
  • Abnormal Uterine Bleeding. Clomiphene is contraindicated in patients with abnormal uterine bleeding of undetermined origin.
  • Ovarian Cysts. Clomid is contraindicated in patients with ovarian cysts or enlargement not due to polycystic ovarian syndrome
  • Clomid is contraindicated in patients with uncontrolled thyroid or adrenal dysfunction or in the presence of an organic intracranial lesion such as pituitary tumor.


    Adverse reactions, side effects:

    Clomid tablets, at recommended dosages, is generally well tolerated. Side effects usually have been mild and transient and most have disappeared promptly after treatment has been discontinued. Adverse experiences reported in patients treated with clomiphene citrate are following:

  • Abdominal-pelvic discomfort/distention/bloating
  • Abnormal uterine bleeding
  • Breast discomfort
  • Headache
  • Nausea and vomiting
  • Ovarian enlargement
  • Vasomotor flushes
  • Visual symptoms


    Drug Interactions:

    Drug interactions with clomiphene have not been documented.


    Pregnancy categories:

  • B3 - Australia
  • X - United States (Should not be used during pregnancy)


    Salts and other forms:

  • Clomiphene Base
  • Clomiphene Citrate


    Synonyms, international and chemical names:

  • Chlomaphene
  • Chloramiphene
  • Cis-Clomifene
  • Cisclomifenum
  • Cisclomiphene
  • Cis-Clomiphene
  • Clomifeen
  • Clomifen
  • Clomifene
  • Clomifeno
  • Clomifenum
  • Clomiphen
  • Clomiphene B
  • Clomiphenum
  • Klomifen
  • Zuclomifene
  • Zuclomifeno
  • Zuclomifenum
  • Zuclomiphene


    Brands, generics, trade names:

  • Clofert - Svizera Healthcare
  • Clomhexal - Hexal, DKSH, Hexanel, Sandoz
  • Clomid - Sanofi-Aventis
  • Clomifen - Leiras
  • Clomifene - Wockhardt
  • Clomifeno - Casen Fleet
  • Clomihexal - Hexal, Sandoz
  • Clomiphen - Arcana Arzneimittel
  • Clomiphene - Par Pharmaceutical, Y.S.P. Industries
  • Clostil - Egis, PharmAsia-Cuvest
  • Clostilbegyt - Egis
  • Duinum - Medochemie, Derek Marketing, Komedic, Medline, Thailand, Star Medical Supplies
  • Fertilan - Codal Synto, CNW Hong Kong, Hong Tai Hong, Star Medical Supplies
  • Fertomid - Cipla
  • Fertyl - Renata, Ar-Ex Laboratories, Euro Generics, Metro Pharma Philippines
  • Genozym - Bristol-Myers Squibb
  • Ikaclomin - Teva
  • Omifin - Sanofi-Aventis, Effik
  • Ovagen - Walter Bushnell
  • Ovamit - Remedica, Pharmadica
  • Ova-Mit - Ebewe Pharma
  • Ovinum - Biolab, Biopharm Chemicals, Indrugco, Medispec
  • Ovofar - Organon
  • Ovulet - Renata, Beracah Pharma Phils, Euro Generics
  • Ovulin - Euro Generics, Marzan Pharma Corporation
  • Pergotime - Serono, Merck
  • Profertil - Kalbe Farma, Apotheca Marketing, Mega Lifesciences
  • Prolifen - Effik
  • Provula - Dexa Medica Pharm & Chem
  • Rejun - Uni Sankyo
  • Serofene - Serono, Novartis
  • Serophene - Serono, Allphar Services, Douglas Pharmaceuticals, Merck, Pharmascience
  • Serpafar - Faran Laboratories
  • Siphene - Serum Institute of India
  • Siphene-M - Serum Institute of India
  • Zimaquin - Recalcine Laboratorios


    APIs used in medicine in combinations with clomiphene:

  • Astaxanthin
  • Folic Acid
  • L-Carnitine
  • L-Arginine
  • Lycopene
  • Methylcobalamin
  • N-Acetylcysteine
  • Ubidecarenone


    Here is a list of popular medications containing clomiphene as a main active pharmaceutical ingredient; their trade names, forms, doses, companies - manufacturers, distributors, suppliers, researchers and developers:

    Trade name of the drug Pharmaceutical forms and doses Companies
    Clomid
  • Tablets; Oral; Clomiphene Citrate 50 mg
  • Sanofi-Aventis
  • DKSH
  • Clostilbegyt
  • Tablets; Oral; Clomiphene Citrate 50 mg
  • Egis
  • Delfi Singapore
  • Medphano Arzneimittel
  • Mekim
  • Pahang Pharmacy
  • Sime Darby Marketing
  • Fertomid
  • Tablets; Oral; Clomiphene Citrate 25 mg
  • Tablets; Oral; Clomiphene Citrate 50 mg
  • Tablets; Oral; Clomiphene Citrate 100 mg
  • Cipla
  • Ova-Mit
  • Tablets; Oral; Clomiphene Citrate 50 mg
  • Ebewe Pharma
  • Corbridge Group
  • Goldplus Universal
  • IDS Group
  • JDH Pharmaceutical
  • Pharmadica
  • Primal Chemical
  • Remedica
  • Ovofar
  • Tablets; Oral; Clomiphene Citrate 50 mg
  • Organon
  • Infar India
  • Serophene
  • Tablets; Oral; Clomiphene Citrate 50 mg
  • Serono
  • Allphar Services
  • Antah Pharma
  • Apex Pharma Marketing
  • DKSH
  • Douglas Pharmaceuticals
  • Four Star
  • Merck
  • Pharmascience



  • References:

  • Clomiphene main article on Wikipedia: https://en.wikipedia.org/wiki/Clomiphene
  • Clomiphene compound on PubChem: https://pubchem.ncbi.nlm.nih.gov/compound/Clomifene
  • Clomiphene Citrate compound on PubChem: https://pubchem.ncbi.nlm.nih.gov/compound/Clomiphene-citrate
  • Clomiphene medicine on DrugBank: https://www.drugbank.ca/drugs/DB00882
  • Clomiphene Citrate on DrugBank: https://www.drugbank.ca/salts/DBSALT000490
  • Clomiphene FAQ on MedlinePlus (revised 09/15/2017): https://medlineplus.gov/druginfo/meds/a682704.html
  • Clomiphene Citrate tablets drug label info on DailyMed (revised August 29, 2019): https://dailymed.nlm.nih.gov/dailymed/drugInfo...
  • Clomiphene containing drugs on Drugs-About.com: https://drugs-about.com/ing/clomiphene.html
  • Clomiphene for sale on Pharma Doctor: https://pharma-doctor.com/clomiphene.html
  • Clomiphene international drug names on Drugs.com: https://www.drugs.com/international/clomifene.html
  • Clomid (Clomiphene Citrate) 50 mg tablets official prescribing information from the U.S. FDA (revised October 2012): https://www.accessdata.fda.gov/drugsatfda_docs/label...
  • Clomid (Clomiphene Citrate) 50 mg tablets product monograph and consumer information from Sanofi-Aventis pharmaceutical company (revised August 9, 2013): https://products.sanofi.ca/en/clomid.pdf
  • Serophene (Clomiphene Citrate) 50 mg tablets product information from GP2U TeleHealth (revised 8 February 2008): https://gp2u.com.au/static/pdf/S/SEROPHENE-PI.pdf
  • Clomid (Clomiphene Citrate) 50 mg tablets patient information leaflet on Medicines.org.uk (revised December 2019): https://www.medicines.org.uk/emc/files/pil.961.pdf
  • Fertomid (Clomiphene Citrate) 25 mg, 50 mg, 100 mg tablets for oral use on Cipla pharmaceutical company website (revised 05 November 2020): https://www.ciplamed.com/content/fertomid-tablets

    Revised: April 2021



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